Scientist

Senior Research Scientist — Vanguard Biopharma

Boston, MA | January 2024 – Present

• Designed and optimized 15 high-throughput screening assays for oncology drug targets, improving biological compound detection sensitivity by 28% and accelerating the lead identification phase by 14 days.
• Secured a $500,000 NIH research grant by presenting key preliminary data on synthetic genetic circuits, reducing subsequent molecular cloning cycle times by 32% over a 9-month project timeline.
• Scaled bioreactor production protocols from 1L benchtop to 50L pilot scale, increasing overall target protein recovery by 22% and reducing batch-to-batch variation rates from 8.4% to 1.5%.
• Supervised 3 junior laboratory technicians on experimental safety and documentation protocols, improving weekly databank upload compliance to 99.4% and eliminating critical auditing blockers.

Research Scientist — Apex Therapeutics

Cambridge, MA | August 2020 – December 2023

• Engineered 12 novel plasmid constructs for mammalian cell transfection using CRISPR-Cas9 genome editing, achieving a gene knockout validation efficiency rate of 94% across all cell lines.
• Managed laboratory chromatography systems (HPLC and GC-MS), reducing annual maintenance downtime by 35% through the implementation of a proactive calibration schedule for 8 systems.
• Co-authored 5 peer-reviewed manuscripts detailing protein purification workflows, which resulted in a 45% increase in citation references within leading biotechnology publications.
• Implemented a digital inventory tracking system for chemical reagents, which reduced annual lab spending on duplicate orders by 18% and saved the research team 5 working hours per week.

High-throughput screening, HPLC, GC-MS, Mammalian cell culture, Western blotting, CRISPR-Cas9, Plasmid design, Protein purification, Benchling, Python (bioinformatics), R (statistics), SQL, Lab safety compliance, Technical writing

OncoScreen Assay Optimization

Role: Lead Biochemist

Tools: HPLC, Benchling, R, Python

Optimized enzyme kinetics assays for a novel kinase inhibitor, increasing screening throughput by 40% and shortening lead validation by 3 weeks.

Metabolic Pathway Engineering Initiative

Role: Research Scientist

Tools: CRISPR-Cas9, Benchling, Python, bioreactor

Redesigned metabolic pathways in yeast hosts, increasing target compound yield by 24% and decreasing raw material consumption by 15%.

• Biosafety Level 2 (BSL-2) Laboratory Director Certification (2021)
• ASCP Technologist in Molecular Biology (MB) (2022)

• Languages: English (Native), Spanish (Conversational)
• Professional Affiliations: Member of the American Chemical Society (ACS)
• Availability: 3 weeks notice